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KMID : 0363220150530100792
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Korean Journal of Dermatology
2015 Volume.53 No. 10 p.792 ~ p.794
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The Malignant Transformation of Sebaceoma into Sebaceous Carcinoma in Nevus Sebaceous
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Lee Hyun-Joo
Kim Won-Jeong
Mun Je-Ho
Kim Hoon-Soo
Ko Hyun-Chang
Kim Byung-Soo
Kim Moon-Bum
Song Margaret
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Abstract
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Nevus sebaceous appears at birth or within the first few months after birth. Secondarily to nevus sebaceous, benign or malignant tumors such as basal cell carcinoma, trichoblastoma, syringocystadenoma papilliferum, squamous cell carcinoma, sebaceoma, and sebaceous carcinoma might occur. Sebaceoma is a benign tumor composed of incompletely differentiated sebaceous cells of varying degrees of maturity. We experienced an uncommon case of malignant transformation of sebaceoma in a 47-year-old man who had a solitary, well-defined, 3.1×2.1 cm sized, round, erythematous nodule on the scalp. Histopathologic examination revealed the presence of irregular lobules of varying size with a well-defined margin from the adjacent interstitial tissue in the dermis. Focally there were atypical cells with a foamy cytoplasm and undifferentiated cells. To the best our knowledge, only one case, from another country, has been reported in the literature. Therefore, we report a very rare case of malignant transformation of sebaceoma that occurred in nevus sebaceous.
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KEYWORD
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Nevus sebaceous, Sebaceoma, Sebaceous carcinoma
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